Nucleic acid amplification testing in Indian blood banks: A review with perspectives
نویسندگان
چکیده
منابع مشابه
Nucleic Acid Amplification Testing: The New Infectious Disease Testing Method for Donor Blood.
Beginning in the spring of 1999, the American Red Cross and 16 member laboratories of the America’s Blood Centers began testing donor blood for the human immunodeficiency virus (HIV) type-1 and the hepatitis C virus with a new research testing method known as nucleic acid amplification testing (NAT). This testing is conducted under well-defined Investigational New Drug research protocols approv...
متن کاملNucleic acid amplification technology for hepatitis B virus, and its role in blood donation screening in blood banks.
OBJECTIVE To investigate the performance of hepatitis B virus polymerase chain reaction (HBV PCR) using one of the commercial methods used around the world to screen for HBV in some blood donors where other conventional serological assays have limitations to detect the virus. METHODS This study was designed to use Amplicor AmpliScreen for HBV testing to detect the presence of the HBV DNA in t...
متن کاملScreening blood donors by nucleic acid amplification technology in Turkey
Volunteer blood donors are screened for hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) infection by various immunoassay methods in Turkey. The risk of enzyme immunoassay (EIA) negative and positive nucleic acid amplification technology (NAT) samples is not clearly understood yet. The purpose of this study is to screen for such donors in Turkey by a comm...
متن کاملNucleic Acid Amplification Testing and Blood Safety: What is the Paradigm?
Over the past 2 decades the pendulum of blood safety policy has swung wide and hit hard. Intense criticism of delayed responses to the early clues of the transfusion AIDS epidemic and of tolerance to the long standing problem of post-transfusion hepatitis has had enormous repercussions.( 1) Blood collection systems in a number of countries have been completely restructured. Policy makers and ph...
متن کاملDigital Nucleic Acid Amplification on a Slipchip
This presentation will describe a recently developed SlipChip based microfluidic platform to perform digital nucleic acid amplification in a simple and low-cost format. Samples can be introduced into the SlipChip by pipetting without the use of complex instruments, and thousands of nanoliter volume compartments can be generated by simple slipping. A “yes-or-no” digital readout of end-point fluo...
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ژورنال
عنوان ژورنال: Indian Journal of Pathology and Microbiology
سال: 2017
ISSN: 0377-4929
DOI: 10.4103/ijpm.ijpm_361_16